The NIH MRI Study of Normal Brain Development: A project sponsored by the National Institutes of Health

Publications

Published papers from the project are available, as listed below:

  1. Albaugh M.D., Ducharme S., Collins D.L., Botteron K.N., Althoff R.R., Evans A.C., Karama S., Hudziak J.J. & Brain Development Cooperative Group. Larger amygdala volume is associated with thinner caudal orbitofrontal cortex: a combination linked to decreased level of emotional control in healthy youths. (submitted)
  2. Almli, C.F., Rivkin, M.H., McKinstry. R.C. & the Brain Development Cooperative Group (2007). The NIH MRI study of normal brain development (Objective-2): Newborns, infants, toddlers, and preschoolers. NeuroImage, 35; 308-325.
  3. Das S., Zijdenbos A.P., Vins D., Harlap J., Evans A.C. (2011). LORIS: A web-based data management system for multi-center studies. Front Neuroinf 5:37.
  4. Ducharme S., Hudziak J.J., Botteron K.N., Albaugh M.D., Nguyen T.V., Karama S., Evans A.C. & Brain Development Cooperative Group (2012). Decreased regional cortical thickness and thinning rate are associated with inattention symptoms in healthy children. J Am Acad Child Adolesc Psychiatry 51(1): 18-27.
  5. Ducharme, S., Hudziak J.J., Botteron K.N., Ganjavi H., Lepage C., Collins D.L., Albaugh, M.D., Evans, A.C., Karama, S. and the Brain Development Cooperative Group (2011). Right anterior cingulate cortical thickness and bilateral striatal volume correlate with Child Behavior Checklist Aggressive Behavior scores in healthy children. Biological Psychiatry, 70(3): 283-290.
  6. Evans, A.C. & the Brain Development Cooperative Group (2006). The NIH MRI study of normal brain development. NeuroImage, 30(1); 184-202.
  7. Fonov, V. Evans, A.C., Botteron, K. Almli, C.R., McKinstry, R.C., Collins, D.L. and the Brain Development Cooperative Group (2011). Unbiased average age-appropriate atlases for pediatric studies. NeuroImage, 54(1); 313-327.
  8. Fu, L., Fonov, V., Pike, B., Evans, A.C. & Collins, D.L. (2006). Automated analysis of multi site MRI phantom data for the NIHPD project. Med Image Comput Comput Assist Interv, 9(Pt 2): 144-151.
  9. Ganjavi H., Lewis J.D., Bellec P., MacDonald P.A., Waber D., Evans A.C., Karama S. & Brain Development Cooperative Group (2011). Negative associations between corpus callosum midsagittal area and IQ in a representative sample of healthy children and adolescents. PLoS ONE 6(5): e19698.
  10. Karama, S., Ad-Dab'bagh, Y., Haier, R.J., Deary, I.J., Lyttelton, O., Lepage, C., Perusse, D., Evans, A.C. and the Brain Development Cooperative Group (2009). Positive association between cognitive ability and cortical thickness in a representative US sample of healthy 6 to 18 year-olds. Intelligence, 37(2); 145-155.
  11. Karama, S., Colom, R., Johnson, W., Deary, I.J., Haier, R., Waber, D.P., Lepage, C., Ganjavi, H., Jung, R., Evans, A.C. and the Brain Development Cooperative Group (2011). Cortical thickness correlates of specific cognitive performance accounted for by the general factor of intelligence in healthy children aged 6 to 18. NeuroImage, 55(4); 1443-1453.
  12. Khundrakpam B., Reid A., Brauer J., Carbonell F., Lewis J., Karama S., Lee J., Chen Z., Evans A.C. (2012). Developmental Changes in Organization of Structural Brain Networks. Cereb Cortex (in press)
  13. Lange, N. & the Brain Development Cooperative Group (2011). Total and regional brain volumes in a population-based normative sample from 4 to 18 years: The NIH MRI Study of Normal Brain Development. Cerebral Cortex, 22;1-12.
  14. Lange N., Froimowitz, M.P., Bigler, E.D., Lainhart, J.E. and the Brain Development Cooperative Group (2010). Associations between IQ, total and regional brain volumes, and demography in a large normative sample of healthy children and adolescents. Dev Neuropsychol, 35(3); 296-317.
  15. Leppert, I.R., Almli, C.R., McKinstry, R.C., Mulkern, R.V., Pierpaoli, C., Rivkin, M.J., Pike, G.B. and the Brain Development Cooperative Group (2009). T(2) relaxometry of normal pediatric brain development. J Magn Reson Imaging, 29(2); 258-267.
  16. Liu, A.K., Marcus, K. J., Fischl, B., Grant, P.E., Poussaint, T.Y., Rivkin, M.J., Davis, P., Tarbell, N.J., and Yock, T. I. (2007). Changes in cerebral cortex of children treated for medulloblastoma. Int J Radiat Oncol Biol Phys, 68(4); 992-998.
  17. Luders, E., Thompson, P.M., Narr, K.L., Zamanyan, A., Chou, Y.Y., Gutman, B., Dinov, I.D. and Toga, A.W. (2011). The link between callosal thickness and intelligence in healthy children and adolescents. NeuroImage, 54(3); 1823-1830.
  18. MacDonald P., Ganjavi H., Karama S., Evans A.C. and Brain Development Cooperative Group. Investigating the relation between basal ganglia volume and IQ. Human Brain Mapping (in review)
  19. Martin, R., Tigera, C., Denckla, M.B. and Mahone, E. M. (2010). Factor structure of paediatric timed motor examination and its relationship with IQ. Dev Med Child Neurol, 52(8); 188-194.
  20. Pangelinan M.M., Zhang G., VanMeter J.W., Clark J.E., Hatfield B.D. & Haufler A.J. (2011). Beyond age and gender: Relationships between cortical and subcortical brain volume and cognitive-motor abilities in school-age children. NeuroImage, 54(4); 3093-3100.
  21. Sanchez, C.E., Richards, J.E., & Almli, C.R. (2012). Neurodevelopmental MRI brain templates for children from 2 weeks to 4 years of age. Dev Psychobiol, 54(1): 77-91.
  22. Waber, C.P., deMoor, C., Forbes, P.W., Almli, C.R., Botteron, K.N, Leonard, G., Milovan, D., Paus, T., Rumsey, J. and the Brain Development Cooperative Group (2007). The NIH MRI study of normal brain development: performance of a population based sample of healthy children aged 6 to 18 years on a neuropsychological battery. J Int Neuropsychol Soc, 13(5); 729-746.
  23. Waber D.P., Forbes P.W., Almli C.R., Blood E.A. & Brain Development Cooperative Group (2012). Four-year longitudinal performance of a population-based sample of healthy children on a neuropsychological battery: the NIH MRI study of normal brain development. J Int Neuropsychol Soc 18(2):179-90
  24. Walker L., Curry M., Nayak A., Lange N., Pierpaoli C. and Brain Development Cooperative Group. A framework for the analysis of phantom data in multicenter diffusion tensor imaging studies. Hum Brain Mapp (epub)
  25. Wels, M. (2010). Probabilistic modeling for segmentation in magnetic resonance images of the human brain. In M. Wels, Probabilistic modeling for segmentation in magnetic resonance images of the human brain, Logos Verlag, Berlin.
  26. Wels, M., Zheng, Y., Carneiro, G., Huber, M., Hornegger, J. & Cormaniciu, D. (2009). Fast and robust 3-D MRI brain structure segmentation. Med Image Comput Comput Assist Interv, 12(Pt 2): 575-583.
  27. Wilke, M., Holland, S.K., Altaye, M., & Gaser, C. (2008). Template-O-Matic: A toolbox for creating customized pediatric templates. NeuroImage, 43(4), 721-730.
  28. Yoon, U., Fonov, V.S., Perusse, D., Evans, AC. and the Brain Development Cooperative Group (2009). The effect of template choice on morphometric analysis of pediatric brain data. NeuroImage, 45(3); 769-777.
  29. Zielinski, B.A., Gennatas, E.D., Zhou, J. and Seeley, W.W. (2010) Network-level structural covariance in the developing brain. Proc Natl Acad Sci USA, 107(42): 18191-18196.
  30. Eskildsen, S.F., Coupe, P., et al. (2012) BEaST: Brain extraction based on nonlocal segmentation technique. NeuroImage 59: 2362-2373.
  31. Sanchez, C.E., Richards, J.E., & Almli, C.R. (2012). Neurodevelopmental MRI brain templates for children from 2 weeks to 4 years of age. Dev Psychobiol, 54(1): 77-91.

Dissertations

  1. Cassidy, A. R. (2010). Unity and diversity of executive functioning across childhood and adolescence: Latent factor structure and associations with subclinical emotional and behavioral problems. Unpublished doctoral dissertation, University of Minnesota, Twin Cities.
  2. Prabhu, D. T2 relaxometry of the human brain between birth and 4.5 years of age. Master's thesis, Boston University. Also presented as a poster at the American Society of Neuroradiology annual meeting, Boston, May 15-20, 2010.

News Articles

  1. Cyranoski, D., NATURE: NIH presents the mind of a child, Vol 447, 24 May 2007

Related Papers

  1. Chang, L.C., Jones, D.K., Pierpaoli, C., 2005. RESTORE: Robust estimation of tensors by outlier rejection. Magnetic Resonance in Medicine 53, 1088-1095.
  2. Rohde, G.K., Barnett, A.S., Basser, P.J., Marenco, S., Pierpaoli, C., 2004. Comprehensive approach for correction of motion and distortion in diffusion-weighted MRI. Magnetic Resonance in Medicine 51, 103-114.
  3. Rohde, G.K., Barnett, A.S., Basser, P.J., Pierpaoli, C., 2005. Estimating intensity variance due to noise in registered images: Applications to diffusion tensor MRI. Neuroimage 26, 673-684.

Abstracts and Presentations

  1. Cassidy, A.R. (June 2011, expected). Associations between executive functions and subclinical emotional and behavioral problems across childhood and adolescence. Poster to be submitted for presentation at the annual meeting of the American Academy of Clinical Neuropsychology, Washington, DC.
  2. Cassidy, A. R. and Crick, N. R. (June 2010). Unity and diversity of executive functions across childhood and adolescence: A latent variable modeling investigation. Poster presented at the annual meeting of the American Academy of Clinical Neuropsychology, Chicago, IL.
  3. Fonov, V.S., Evans, A.C., McKinstry, R.C., Almli, C.R. and Collins, D.L. (2009). Unbiased nonlinear average age-appropriate brain templates from birth to adulthood. Organization for Human Brain Mapping Meeting, Neuroimage, 47 (suppl 1), S102.
  4. Haufler, A. J., Pangelinan, M. M., Zhang, G., VanMeter, J., Clark, J. E. and Hatfield, B. D. (June 2010). An examination of cognitive-motor ability and structural brain changes in typically developing children. Paper presented to the annual meeting of the American College of Sports Medicine, Baltimore, MD. Medicine and Science in Sports and Exercise, 42(5 Supplement), 2530.
  5. Haufler, A.J., Pangelinan, M.M., Zhang, G., Van Meter, J.W., Clark, J.E., and Hatfield, B.D. (November 2009). Brain development and motor ability: the relationship among age, gender, IQ, and the Perdue Pegboard task. Paper presented to the Mid-Atlantic Chapter of the American College of Sports Medicine, Harrisburg, PA.
  6. Nayaj, A., Walker, L., Pierpaoli, C. and the Brain Development Cooperative Group (2011). Quality assessment in a DTI multicenter study. ISMRM.
  7. Pangelinan, M.M., Zhang, G., Van Meter, J.W., Clark, J.E., Hatfield, B.D. and Haufler, A.J. (October 2009). Developmental differences in regional brain volumes are related to age, gender, IQ and visuomotor performance. Paper presented at the School of Public Health Research Interaction Day, College Park, MD.
  8. Pangelinan, M.M., Zhang, G., Van Meter, J.W., Clark, J.E., Hatfield, B.D. and Haufler, A.J. (July 2009). Developmental differences in regional brain volumes are related to age, gender, IQ and visuomotor performance. Presented at the Conference on Neurocognitive Development, Berkely, CA.
  9. Richards, J.E. (2010). What's inside a baby's head? Structural and functional brain development in infants. International Conference on Infant Studies, Baltimore, MD, March 2010.
  10. Sanchez, C.E., Richards, J.E., and Almli, C.R. (2010). A neurodevelopmental MRI database for infants. International Conference on Infant Studies, Baltimore, MD, March 2010.
  11. Walker, L., Lange, N., Chang, L-C., Pierpaoli, C. and the Brain Development Cooperative (2011). A framework for analysis of living phantom data in a multicenter DTI study. ISMRM
  12. Zielinski, B.A., Gennatas, E.D., Zhou, J. and Seeley, W.W. (2010). Network-level structural covariance in the developing brain. Presented at the American Academy of Neurology Annual Meeting, Toronto, Canada, April 2010.